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Pulmonary hypertension (PH) describes a group of chronic devastating diseases, which cause breathlessness and premature death. Extensive lung vascular remodelling with loss of vessel patency is the underlying pathomechanism in PH. PULMOTENSION integrates the top European Centres in PH and lung vascular biology in a multidisciplinary approach, with the aim to combat PH.We intend to uncover molecular pathways, identify distinct targets for anti-remodelling therapy, foster drug development based on these targets, and then test these new treatment options in preclinical and clinical trials (“from bench to bedside”).

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